Jose Paniagua spent parts of 8 seasons in the major leagues, and exactly one game, his final one as it turns out, with the 2003 Chicago White Sox.  He lasted one third of an inning against the Twins, giving up 3 hits, 1 walk, and 4 earned runs, finishing with a 108.00 ERA.  After then-manager Jerry Manuel mercifully removed him from the game, Paniagua went out with style by flipping off an umpire on his way off the field.  He was released the next day.

The only time I saw him pitch in person was against the White Sox as a member of the Mariners in the 2000 ALDS.  In that appearance, he managed to only give up 1 hit and 1 walk over 2 innings.